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Product Info

Each tablet of Excedrin contains three active substances:
acetylsalicylic acid (aspirin), paracetamol and caffeine.

Acetylsalicylic acid (aspirin) and paracetamol reduce pain and fever, and acetylsalicylic acid (aspirin) also reduces inflammation.
Caffeine is a mild stimulant and increases the effect of acetylsalicylic acid (aspirin) and paracetamol.

Excedrin is used for the acute treatment of headache and migraine attacks (symptoms such as headache, nausea, sensitivity to light and sound and functional disability) with or without aura.

Suitable for

Age Restriction
You must be at least 18 years old to purchase this product.

How to use

Patient Information Leaflets are updated periodically by the manufacturer.
Please read the enclosed leaflet carefully before use.


Always take Excedrin exactly as stated in this package leaflet or as your doctor or pharmacist has told you. You should check with your doctor or pharmacist if you are not sure.

Adults (18 years of age and older):

For headache treatment:

Take 1 tablet with a full glass of water when headache pain appears.

If needed, you can take another 1 tablet 4 to 6 hours later.
In case of more intense pain, take 2 tablets with a full glass of water when headache pain appears. If needed, you can take another 2 tablets 4 to 6 hours later.
Do not use Excedrin for more than 4 days for headache without consulting your doctor.

For migraine treatment:

Take 2 tablets with a full glass of water when migraine symptoms or migraine aura appear. If needed, you can take additional 2 tablets, with 4 to 6 hours between doses.
If you get no migraine relief within 2 hours from the first 2-tablet dose of Excedrin, you should seek the advice of a doctor.
Do not use Excedrin for more than 3 days for migraine without consulting your doctor.

For both headache and migraine treatment, do not exceed 6 tablets over a period of 24 hours. This corresponds to a dose of 1500 mg acetylsalicylic acid (aspirin), 1500 mg paracetamol and 390 mg caffeine.

Prolonged use except under medical supervision may be harmful.

Do not take more than the stated dose. Use the smallest dose that you need to treat your symptoms and use this medicine for the shortest period of time necessary.

Children and adolescents:
Excedrin should not be given to children and adolescents under the age of 18 (see patient information leaflet)

Warning - Do not exceed stated dose

Hazards and Cautions

Consult your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, complementary therapies or if you have a medical condition. This medicine may not be suitable for you if you have a medical condition or taking any medications such as those listed in the Patient Information Leaflet. Please refer to the Patient Information Leaflet for further warnings, precautions, side effects and instructions for use for this product.

Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage.


Consult your doctor or pharmacist if symptoms persist or get worse at any stage.

Seek advice before using if you are pregnant, planning to become pregnant, breastfeeding or suffer from allergies.


Do not use Excedrin after the expiry date which is stated on the blister and carton after EXP. The expiry date refers to the last day of that month.

Do not store above 25 °C.

Keep all medicines out of the sight and reach of children

Active ingredients

One film-coated tablet contains 250 mg acetylsalicylic acid, 250 mg paracetamol and 65 mg caffeine


Tablet core: hydroxypropyl cellulose low substitution, cellulose microcrystalline (E460), stearic acid. Film-coating: hypromellose (E464), titanium dioxide (E171), propylene glycol, benzoic acid (E210), carnauba wax (E903).

Free Click & Collect

We offer a FREE click and collect service through our retail store:

O'Casey's Pharmacy,
Unit 2, Block 2,
Island Key,
D03 E6C3

Telephone: +353 1 908 9308

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